Peng Zhan Selected Research

1- (3,4- dihydroxyphenyl)- 2- ((1- mesityl- 1H- imidazo(4,5- c)pyridin- 2- yl)thio)ethanone

7/2014

Discovery and characterization of novel imidazopyridine derivative CHEQ-2 as a potent CDC25 inhibitor and promising anticancer drug candidate.

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Peng Zhan Research Topics

Disease

17	Human Influenza (Influenza) 12/2023 - 06/2012
16	Neoplasms (Cancer) 02/2024 - 09/2013
14	Acquired Immunodeficiency Syndrome (AIDS) 04/2024 - 10/2008
13	Infections 04/2024 - 02/2010
8	COVID-19 01/2023 - 11/2020
7	Virus Diseases (Viral Diseases) 01/2024 - 01/2011
6	Gout 03/2024 - 09/2017
6	Hyperuricemia 03/2024 - 11/2019
6	Breast Neoplasms (Breast Cancer) 11/2023 - 12/2014
4	Alzheimer Disease (Alzheimer's Disease) 12/2023 - 01/2018
3	autosomal dominant Spastic paraplegia 6 08/2022 - 10/2020
3	HIV Infections (HIV Infection) 04/2016 - 01/2009
2	Metabolic Diseases (Metabolic Disease) 03/2024 - 09/2023
2	Hepatocellular Carcinoma (Hepatoma) 02/2024 - 01/2019
2	Atrophy 09/2023 - 12/2019
2	Bites and Stings (Sting) 09/2023 - 01/2023
2	Vesicular Stomatitis 01/2022 - 12/2020
2	Hepatitis B 11/2020 - 09/2020
2	Wounds and Injuries (Trauma) 01/2020 - 01/2019
2	Drug-Related Side Effects and Adverse Reactions 01/2018 - 01/2010
2	Neoplasm Metastasis (Metastasis) 04/2016 - 12/2014
1	Urinary Tract Infections (Urinary Tract Infection) 04/2024
1	Schizophrenia (Dementia Praecox) 02/2024
1	Cognitive Dysfunction 02/2024
1	Catalepsy 02/2024
1	Liver Neoplasms (Liver Cancer) 02/2024
1	Osteoporosis 12/2023
1	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2023
1	Fibrosis (Cirrhosis) 09/2023
1	Insulin Resistance 09/2023
1	Sarcopenia 09/2023
1	Melanoma (Melanoma, Malignant) 04/2023
1	Chronic Hepatitis B 01/2023
1	Invasive Fungal Infections 01/2023

Drug/Important Bio-Agent (IBA)

14	Antiviral Agents (Antivirals)IBA 01/2024 - 01/2010
9	Proteins (Proteins, Gene)FDA Link 04/2024 - 01/2011
9	Oseltamivir (Tamiflu)FDA Link 12/2023 - 02/2018
7	Uric Acid (Urate)IBA 03/2024 - 09/2017
6	Neuraminidase (Sialidase)IBA 12/2023 - 02/2018
5	Reverse Transcriptase InhibitorsIBA 03/2024 - 09/2010
5	Anti-HIV Agents (AIDS Drugs)IBA 10/2022 - 10/2008
4	NucleosidesIBA 03/2024 - 02/2010
4	InterferonsIBA 09/2023 - 11/2020
4	lesinuradIBA 12/2022 - 09/2017
3	Human immunodeficiency virus 1 reverse transcriptaseIBA 04/2023 - 08/2022
3	ButyrylcholinesteraseIBA 01/2023 - 01/2018
3	EndonucleasesIBA 02/2019 - 11/2017
2	PyrazinesIBA 12/2023 - 12/2023
2	Biomarkers (Surrogate Marker)IBA 12/2023 - 04/2016
2	Histones (Histone)IBA 11/2023 - 09/2013
2	EnzymesIBA 04/2023 - 07/2014
2	Circular DNAIBA 01/2023 - 11/2020
2	urate transporterIBA 12/2022 - 10/2020
2	AnionsIBA 12/2022 - 11/2019
2	VaccinesIBA 04/2022 - 11/2020
2	Poly I-CIBA 01/2022 - 12/2020
2	CarbonIBA 03/2021 - 10/2020
2	oseltamivir carboxylateIBA 02/2020 - 06/2012
2	Ion Channels (Ion Channel)IBA 04/2016 - 12/2014
2	Vorinostat FDA Link 04/2016 - 12/2014
2	Histone Deacetylases (Histone Deacetylase)IBA 04/2016 - 12/2014
2	Histone Deacetylase InhibitorsIBA 04/2016 - 12/2014
2	Ribavirin (Virazole)FDA LinkGeneric 10/2015 - 06/2012
2	Amantadine (Aman)FDA LinkGeneric 10/2015 - 06/2012
2	Rimantadine FDA LinkGeneric 10/2015 - 06/2012
2	Integrase InhibitorsIBA 04/2013 - 01/2009
1	16S Ribosomal RNAIBA 04/2024
1	Anti-Bacterial Agents (Antibiotics)IBA 04/2024
1	Vancomycin FDA LinkGeneric 04/2024
1	GlycopeptidesIBA 04/2024
1	Antipsychotic Agents (Antipsychotics)IBA 02/2024
1	Trace amine-associated receptor 1IBA 02/2024
1	AminesIBA 02/2024
1	Sialic Acid Binding Immunoglobulin-like LectinsIBA 02/2024
1	Chemokine ReceptorsIBA 12/2023
1	Maraviroc FDA Link 12/2023
1	Chalcone (Benzalacetophenone)IBA 12/2023
1	Protein Isoforms (Isoforms)IBA 11/2023
1	Histone Deacetylase 1IBA 11/2023
1	Immunoglobulins (Immunoglobulin)IBA 11/2023
1	MucinsIBA 11/2023
1	Fatty Acids (Saturated Fatty Acids)IBA 09/2023
1	Insulin (Novolin)FDA Link 09/2023
1	Proteasome Endopeptidase Complex (Proteasome)IBA 09/2023
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 09/2023
1	CoumarinsIBA 04/2023
1	Melanins (Melanin)IBA 04/2023
1	coumarinIBA 04/2023
1	Oxidoreductases (Dehydrogenase)IBA 04/2023
1	Monophenol Monooxygenase (Tyrosinase)IBA 04/2023
1	ChemokinesIBA 01/2023
1	Amino Acids FDA Link 01/2023
1	NucleotidesIBA 01/2023
1	Peptides (Polypeptides)IBA 01/2023
1	nirmatrelvirIBA 01/2023
1	CytokinesIBA 01/2023

Therapy/Procedure

21	Therapeutics 02/2024 - 01/2011
3	Highly Active Antiretroviral Therapy (HAART) 11/2017 - 01/2009
2	Immunotherapy 02/2024 - 11/2023
2	Drug Therapy (Chemotherapy) 01/2009 - 10/2008